mavorixafor will increase the level or effect of codeine by affecting hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a powerful CYP2D6 inhibitor) is contraindicated with medicine which can be really dependent on CYP2D6 for clearance.There are various other PDE5 inhibitors as well as other ED medicines Which might be handy in the ev